Application of Marijuana in Medicinal use for Epilepsy

Introduction 

There are two types of marijuana THC and CBD they are classified cannabinoids. They are hooked to receptors in the brain they act against conditions susceptible to pain, like sclerosis and HIV/AIDS. By hooking to receptors, they inhibit the transmission of pain stimuli. CBD hooks to higher than just pain receivers. It actions on other stimulating receptors in the brain and has preservatory and anti-swelling actions. 

 Medical Marijuana uses for epilepsy are cannabis products of high  assay in Δ(9) – tetrahydrocannabinol (THC), applied primarily for entertainment purposes, are generally unsuitable for this purpose , basically because THC is affiliate to a lot of side effects. Comparative to THC, Cannabidiol(CBD) shows a better configurationally anticonvulsant characteristic in animal taxonomy and is absent of adverse psychoactive activity and misuse liability. Over a long period, this has led to an escalating usage of CBD-enriched distillate in seizure disorders, especially in children.  

Mode of action 

The genus Cannabis refers to a blossoming plant that three main genre, Cannabis indica Cannabis sativa and Cannabis ruderalis. Raw preparations of cannabis entails dried leaves, trunk and flower pods (marijuana), balms (hashish), and oily compounds (hashish oil), that has all   been used through the ages mainly for their psychoactive activity. Basically, cannabis yields sourced from Cannabis sativa exhibits a spiked CBD/THC portion than yields sourced from Cannabis indica. Variety Cannabis species have been bred either to spike THC assay or, alternatively, to degrees THC assay and spike the concentration of CBD and variety non-psychoactive assay. 

Cannabinoids have enormous and intricate pharmacological activities. Models, for example, THC shows intricate psychoactive activities, variety anticonvulsant activities, and anti-pain, mental, muscle relaxant, anti-swelling, appetite stimulant, and antiemetic activity. While on one hand, CBD is mainly free of adversative psychoactive activity and has anticonvulsant, pain killer, anti-anxiety, antiemetic, immune-controller, anti-swelling, neuroprotectant, and anti-tumorigenic activity. For this matter THC, anti-seizure activity seems to be arbitrated to an important scope by its partial agonist activity on the CB1 receptor, which is also primarily involved in the manifestation of psychoactive effects. CBD, while on the other hand, it has very feeble affinity for the CB1 and CB2 indicators and its anti-seizure activity at clinically pertinent assay is considered to be arbitrated by different mechanisms 

Conclusion 

The legal provisions banning the growth of Medical Marijuana uses for epilepsy should be moderated to factor in its benefits medically that alleviate mankind infirmities like epilepsy which has been stigmatized in some communities.